QT interval variables from 24 hour electrocardiography and the two year risk of sudden death.

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QT interval variables from 24 hour electrocardiography and the two year risk of sudden death.

OBJECTIVE To study the effects of variability in the duration of the QT interval corrected for heart rate (QTc) on the occurrence of sudden death. DESIGN Nested case-referent study. SUBJECTS Cohort of 6693 consecutive patients who underwent 24 hour electrocardiography and were followed up for two years. Risk implications of QTc interval variables were studied in patients without evidence of...

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Heart Rate Variabilit From 24-Hour Electrocardiography and the 2-Year Risk for Sudden Death

Background. Low heart rate variability has been implicated as a risk factor for sudden death. However, no large epidemiological studies using sudden death as an outcome event have been reported. Methods and Results. A total of 6,693 consecutive patients who underwent 24-hour ambulatory ECG were followed up for 2 years; of these, 245 patients died suddenly. Clinical data at the time of 24-hour a...

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Heart rate variability from 24-hour electrocardiography and the 2-year risk for sudden death.

BACKGROUND Low heart rate variability has been implicated as a risk factor for sudden death. However, no large epidemiological studies using sudden death as an outcome event have been reported. METHODS AND RESULTS A total of 6,693 consecutive patients who underwent 24-hour ambulatory ECG were followed up for 2 years; of these, 245 patients died suddenly. Clinical data at the time of 24-hour a...

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Diagnostic performance of QT interval variables from 24-h electrocardiography in the long QT syndrome.

AIMS The long QT syndrome is mainly defined by QT interval prolongation (QTc > 0.44s). However, data obtained in genotyped patients showed that resting QTc measurement alone may be inaccurate for ascertaining the phenotype. The aim of this study was to evaluate the diagnostic performance of QT interval rate-dependence in untreated chromosome 11-linked patients. METHODS The study population co...

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Genetic determinants of QT interval variation and sudden cardiac death.

Electrocardiographic QT interval prolongation or shortening is a risk factor for sudden cardiac death. The study of Mendelian syndromes in families with extreme long and short QT interval duration and ventricular arrhythmias has led to the identification of genes encoding ion channel proteins important in myocardial repolarization. Rare mutations in such ion channel genes do not individually co...

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ژورنال

عنوان ژورنال: Heart

سال: 1993

ISSN: 1355-6037

DOI: 10.1136/hrt.70.1.43